Frequent oral thrush in asthma/COPD patients! What could be the reason?

Have you come across asthma patients, or COPD patients who keep complaining about oral fungal infections?

Patients suffering from asthma, COPD or HIV are commonly prescribed inhaled corticosteroids (ICSs); however, long term usage of ICSs causes local immunosuppression in oral cavity which in turn results in development of oropharyngeal candidiasis, a fungal infection primarily caused by Candida albicans. Key risk factors include high ICS doses, poor oral hygiene and improper use of inhalers.

I remember a patient frequently complaining of oral thrush, and that would result in additional medications to treat the same. This caused a loop of treating side effects of standard treatment protocols. However, prevention plays a crucial role in overcoming the side effects of prolonged use of ICSs particularly by focusing on patient education.

Some of the simple yet effective preventive measures include:

  • Oral Hygiene: Remember to instruct the patients to rinse the mouth properly, ensure that the patient gurgles and swishes the water 2 to 3 times after using inhalers.
  • Cleaning the Equipments: Instruct the patient to clean the Equipments regularly be it the nebulizer, or simply the pump.
  • Tooth Brush: Instruct patients to maintain oral hygiene by brushing twice daily using appropriate toothpaste.

This list is not exhaustive, please check this link for more information Non-Pharmacological Interventions to Prevent Oropharyngeal Candidiasis in Patients Using Inhaled Corticosteroids: A Narrative Review - PMC Non-Pharmacological Interventions to Prevent Oropharyngeal Candidiasis in Patients Using Inhaled Corticosteroids: A Narrative Review - PMC

Have you encountered a patient complaining of oral thrush or maybe someone you know struggles from this issue? What are your thoughts about it and what more can be done by adopting preventive measures.

MBH/PS

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I remember encountering one such patient with a severe case of oral candidiasis on the palate. The patient was using a complete denture fabricated a long time ago. The patient has never removed it since then to even clean it because apparently the QUACK who fabricated it said, it’s fixed for life and should never be removed!

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Yes, it’s unfortunate sometimes miscommunication or misinformation that leads to such incidents.