Have you ever wondered how a disease develops and spreads within a community?
In Public Health and Community Medicine, this process is explained through the Natural History of Disease, which helps us understand not just individual illness but the broader patterns of disease in populations. Pathogenesis or spread of disease is divided into two key phases:
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Pre-pathogenesis Phase:
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Interaction occurs between the agent, host, and environment before the onset of disease, meaning risk factors are already present, but the disease itself has not yet developed.
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At this stage, primary level of prevention is taken into account.
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Pathogenesis Phase:
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This phase represents the stage where risk factors persist and the disease has already begun to manifest and spread.
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It includes two stages — early pathogenesis (presymptomatic) and late pathogenesis (clinical). The former is characterized by the presence of both risk factors and disease, but without visible signs or symptoms, while the latter involves the presence of risk factors, disease, and evident disability or clinical manifestations.
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During the early pathogenesis stage, secondary prevention is implemented, whereas in the late pathogenesis stage, tertiary prevention proves to be more effective.
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To combat disease effectively, we focus on four levels of prevention:
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Primordial Prevention: Preventing the emergence of risk factors.
- Education
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Primary Prevention: Stopping disease before it starts (e.g., vaccination, sanitation).
- Health promotion: Health education, Environmental modification, Nutritional intervention, Lifestyle & behavioral changes.
- Specific protection: Mass strategy, High risk strategy.
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Secondary Prevention: Action taken to halt the progress of disease at initial stage.
- Early diagnosis: Screening test, Diagnostic tests.
- Treatment: Mass treatment.
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Tertiary Prevention: Action taken to limit impairment and disabilities.
- Disability limitation
- Rehabilitation
Prevention is not just about cure—it’s about breaking the chain of disease progression before it even begins.
MBH/AB