Ergots cause dry gangrene so should we prescribe to migraine patient…??
Discuss it.
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Ergots are still applicable in select migraine patients but are no longer rarely first-line due to the risk of severe side effects such as dry gangrene. There are safer alternatives, and ergot derivatives must be reserved for special cases under close medical supervision.
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Could you please share some information about what are Ergots ?
Ergots are partial agonists or antagonists at multiple receptors:
Serotonin receptors (5-HT1, 5-HT2)
Dopamine receptors
Adrenergic receptors
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We have other safe and effective options available so we can opt them
Ergotamines can cause vasoconstriction, potentially leading to gangrene. Prescribing them for migraines requires caution. Patients with vascular risk factors should avoid ergotamines. Alternative treatments like triptans may be safer. Close monitoring is essential for patients on ergotamines. Careful patient selection is crucial to minimize risks.
It can be taken but not frequently and only during early migrane attacks dude to it’s adverse effects
many researches shows the useful of ergot for many diseases.