Resistance disasters

Antibiotic resistance has been a problem for a while now.
The failure of sticking to the prescribed regimen and/or self medicating are the top reasons known.
The vast variety and classes of antibiotics vary on the basis of chemical structures, metabolism of action, clearance rates etc.
What are some ways of preventing antibiotics misuse?
What are the steps to be taken for a patient who is to be treated for an infection after long term antibiotics misuse?

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