An 82-year-old hypertensive and diabetic patient on amlodipine, metformin, and warfarin presents with unexplained bruising and elevated INR after starting an antibiotic for a urinary tract infection.
How would you identify the potential drug interaction, adjust the therapy, and monitor the patient to prevent further complications?
The antibiotic likely potentiated warfarin, causing bleeding and high INR.
Adjust warfarin dose, switch antibiotics if needed, and monitor INR closely. Patient safety is paramount here, preventing serious complications.