Case - Based Discussion: Pregnancy, Hypercoagulability and DVT"

“A Swollen Leg After Delivery”: A Case - Based Insight into DVT in Pregnancy

A 28-year-old woman, 5 days after cesarean section, arrives at the emergency department complaining of pain and swelling in her left leg. She says she thought it was “normal weakness after delivery,” but the swelling gradually worsened. She also mentions mild breathlessness while climbing stairs.

On examination:

  • Left calf is swollen and tender
  • Mild redness present
  • Pulse rate elevated
  • Oxygen saturation slightly reduced

A doppler ultrasound later confirms Deep Vein Thrombosis (DVT).

This case highlights an important reality in obstetric medicine:

Not every swollen leg during or after pregnancy is “normal pregnancy edema”.

Why does pregnancy increase DVT risk?

Pregnancy naturally creates a hypercoagulable state:

  • Increased clotting factors
  • Reduced venous return
  • Hormonal vascular changes
  • Relative immobility after delivery

The physiological adaptation protects against hemorrhage during childbirth, but it also increases thrombosis risk.

Why is the left leg more commonly affected?

The enlarging uterus compresses the left iliac vein more commonly than the right, causing venous stasis in the left lower limb.

Important risk factors in this patient:

  • Cesarean section
  • Postpartum immobility
  • Possible dehydration
  • Physiological hypercoagulability

The dangerous part:

If the clot dislodges and travels to lungs, it can cause pulmonary embolism, one of the leading preventable causes of maternal mortality.

Clinical learning point:

Symptoms of DVT can mimic normal pregnancy discomfort:

  • Leg heaviness
  • Swelling
  • Fatigue
  • Calf pain

Because of this overlap, diagnosis is often delayed.

Diagnostic approach:

  • Compression stockings
  • Clinical risk assessment
  • D-dimer interpretation becomes difficult during pregnancy due to naturally elevated levels

Treatment:

Heparin or LMWH heparin are commonly preferred because they are safer in pregnancy.

Warfarin is usually avoided during pregnancy due to fetal risks.

Prevention matters:

  • Early mobilization after delivery
  • Hydration
  • Compression stockings in high - risk women
  • Antenatal thrombotic risk assessment

Clinical discussion points:

  1. How would you clinically differentiate normal pregnancy edema from suspected DVT?
  2. How does a cesarean section increase thrombotic risk?
  3. Can anxiety and fear during pregnancy indirectly worsen DVT risk through reduced mobility?
  4. As future doctors, how do we balance reassurance with early suspicion in obstetric emergencies?

MBH/PS

Well explained