A 65-year-old woman with atrial fibrillation is started on warfarin. On the 4th day of treatment, she develops a painful, purple discoloration over her thighs and breasts. Labs show a low protein C level.
What is the most likely cause of this complication?
A) Heparin-induced thrombocytopenia
B) Warfarin-induced skin necrosis
C) Allergic dermatitis
D) Antiphospholipid syndrome