Laminin is a protein that is present in the human placenta. Polylaminin is the polymer of that protein. This polymer is showing a significant effect on damaged nerve fibers of the spinal cord. It helps to regrow the axon. This was developed by Dr. Tatiana Coelho de Sampaio at the Federal University of Rio de Janeiro (UFRJ) in Brazil.
How to use Polylaminin in Spinal Cord Injury?
It is surgically injected into the injury site within 24 -72 hours of the injury.
Does it work on humans?
It shows a promising result on both animals and humans. Phase 1 trial is conducted in Brazil in collaboration with the pharmaceutical company Cristália. As the trial is ongoing, the final safety report has not been published, but the early data and pilot studies are showing significant results. Further trials will be performed to ensure the efficacy and safety of the therapy.
I genuinely enjoyed reading this because I learned something completely new today. It’s incredible how a protein from the human placenta could potentially contribute to spinal cord repair. Looking forward to seeing how the ongoing clinical trials progress.
This is fascinating. It’s encouraging to see research moving beyond symptom management and exploring ways to actually promote nerve regeneration. I’ll be interested to see how the ongoing clinical trials progress.
Absolutely fascinating…thank you for sharing! The idea of using a placenta-derived polymer like Polylaminin to help regrow axons is mind-blowing!!! Regenerative medicine like this could completely change the landscape for spinal cord injury care… Excited to see how the safety report turns out!!
I had never come across polylaminin before, and this was a really interesting introduction. The possibility of promoting axon regeneration after a spinal cord injury is remarkable. I’m curious to see how the ongoing clinical trials shape the future of this therapy.
