Pharmacology Quiz on Phenytoin

General
1

Which of the following drugs is most commonly associated with causing gingival hyperplasia?

A. Phenytoin
B. Amiodarone
C. Propranolol
D. Digoxin

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2

The drug most commonly associated with causing gingival hyperplasia is:
A. Phenytoin
Reason- Phenytoin, an anticonvulsant is known for this side effect. Gingival hyperplasia involves an overgrowth of the gum tissue and is a well-documented adverse effect of long-term phenytoin use.

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Option A. Phenytoin.

4

Is there any mechanistic relation b/w them

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Yes, @Jeevitha there is a mechanistic link. Phenytoin stimulates certain cells in the gums called fibroblasts which produce excess collagen. This leads to the thickening and overgrowth of gum tissue especially with poor oral hygiene. So, the drug and the body’s response together cause gingival hyperplasia.

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Thanks for the clarification

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A. Phenytoin

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Phenytoin is most commonly associated with causing gingival hyperplasia.

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Option A

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Phenytoin is associated with causing gingival hyperplasia, a side effect involving overgrowth of gum tissue.

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Phenytoinis the drug which is commonly associated with gingival hyperplasia. It is caused due to the direct action of phenytoin on the high activity fibroblast present in the gingiva causing increased collagen production.

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Phenytoin

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Phenytoin

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Phenytoin

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Ginigival hyperplasia is a side effect of several drugs.
while the option A Phenytoin is an anticonvulsant most classic cause

correct option A phenytoin

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Option A - Phenytoin

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Phenytoin

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Phenytoin anticonvulsant drug causes gingival hyperplasia

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It’s Phenytoin

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Phenytoin