Irritable bowel syndrome (IBS) is a complex and highly prevalent disorder of gut-brain interaction (DGBI), characterized by recurrent abdominal pain and altered bowel habits, including constipation, diarrhea, or a combination of both.
The pathophysiology of IBS is multifactorial, involving disruptions in the gut-brain axis, visceral hypersensitivity, gastrointestinal dysmotility, alterations in gut microbiota, food intolerances, and psychosocial factors. It does not involve visible inflammation or permanent damage to the digestive tract. IBS affects 10-15% of people worldwide.
Symptoms include
Abdominal pain or cramping
Bloating
Diarrhea, constipation, or alternating between both
Gas and changes in bowel habits
Common myths associated with IBS include
IBS is inflammatory bowel disease (IBD)
IBD includes conditions like Ulcerative Colitis and Crohn’s Disease. Both are inflammatory and causes structural changes in intestinal lining
There is no inflammation in IBS
It’s just stress
Stress worsens symptoms but does not cause the disorder, which involves gut flora changes and sensitivity.
IBS leads to colon cancer.
IBS is a functional disorder and does not increase the risk of malignancy.
Everyone with IBS should avoid the same foods
Triggers are different for everyone.
Common triggers include:
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Dairy
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Fatty or fried foods
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Caffeine
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Artificial sweeteners
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High-FODMAP foods
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IBS has no cure but it is manageable. A low-FODMAP diet is a three-phase elimination, reintroduction, and personalization approach commonly used to manage IBS. FODMAP stands for Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols which are types of short-chain carbohydrates (sugars) that the small intestine absorbs poorly.