Drug of the Week series

A 35-year-old patient with long-standing rheumatoid arthritis is not responding adequately to methotrexate therapy. The physician decides to add infliximab to the treatment regimen.

:red_question_mark: Why is infliximab often combined with methotrexate in rheumatoid arthritis?

:radio_button: A. To reduce antibody formation against infliximab

:radio_button: B. To increase renal excretion

:radio_button: C. To prevent gastric irritation

:radio_button: D. To improve oral absorption

Can you name other diseases where TNF-ฮฑ inhibitors like infliximab are used?

MBH/PS

Correct option is A.

Other diseases are:
Crohnโ€™s Disease ,Ulcerative Colitis , Psoriasis, Psoriatic Arthritis ,Ankylosing Spondylitis, Juvenile Idiopathic Arthritis.

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Option A.

Infliximab is a monoclonal antibody and acts as an anti TNF- alpha medication. Commonly used in Chrohโ€™s disease, ulcerative colitis and ankylosing spondylitis.

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Ans is A to reduce antibody formation
Other conditions like crohnโ€™s disease, ulcerative colitis, arthritis infliximab can be used .

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Thank you for sharing this. Conditions like ankylosing spondylitis can be challenging, and therapies like infliximab truly give hope by helping control chronic inflammation and improve quality of life. Wishing you strength on your journey :white_heart: