Drug of the week series - 28.1

A 32 year old male presents to the emergency department with severe vomiting, abdominal pain, hypotension, and confusion. He has a history of chronic adrenal insufficiency and missed his steroid doses for several days. Which drug should be administered immediately?

Drug of the week series
  • Prednisolone
  • Hydrocortisone
  • Dexamethasone
  • Fludrocortisone
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MBH/PS

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Instead of oral; IV route is preferred

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Hydrocortisone provides immediate glucocorticoid replacement and has sufficient mineralocorticoid activity at stress doses.