DRESS syndrome!

What is DRESS syndrome?

A severe allergic reaction that can affect multiple body systems.

• Common symptoms include:

- Skin rash

- Fever

- Lymph node swelling (lymphadenopathy)

- Blood anomalies (eosinophilia)

- Organ complications (liver, kidney, etc.)

  • It can appear 2–8 weeks after starting the medication.
  • Potentially serious, with a mortality rate of up to 10%.

1. What medications can trigger DRESS syndrome?

2. How can DRESS syndrome be treated if symptoms appear?

MBH/AB

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Always monitor for unusual reactions when starting new medications and seek prompt medical help—early detection can save lives.

Seek medical attention

Mefenamic acid is one such drug that can cause DRESS syndrome. In 2023, the FDA has issued safety alert for enhanced vigilance for this drug.

If you see any other reaction or side effects, you should go early diagnosis which helps in prevention of any major health issues

Mefenamic acid can cause dress syndrome.

Well explained!

Common drug triggers include anticonvulsants (phenytoin, carbamazepine, lamotrigine), sulfonamides, allopurinol, and certain antibiotics.

Management primarily involves immediate discontinuation of the offending drug, supportive care, and in severe cases, systemic corticosteroids under close monitoring.

Informative, If such symptoms appear- the first step is to stop the suspected drug and seek medical supervision immediately.

DRESS syndrome stands for Drug Reaction with Eosinophilia and Systemic Symptoms.

A rare but dangerous drug reaction known as “DRESS syndrome” might appear weeks after beginning to use a particular medication. It can harm organs including the liver or kidneys and results in rash, fever, enlarged lymph nodes, and elevated eosinophils. Early detection and drug cessation can save lives.

Why is it called “dress syndrome”? Is there any story behind it? Would love to know your thoughts.