Again a disease Myasthenia Gravis.
What is it?
Cause?
Did you hear about “
Ice Pack test” for myasthenia??
Let’s discuss…
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It causes weakness in the muscle of body.
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Myasthenia Gravis is a chronic autoimmune disease where the body’s immune system blocks the communication between nerves and muscles, causing weakness and fatigue, especially in the eyes, face, and throat. It happens because antibodies attack the receptors that help muscles contract.
Yes! The Ice Pack Test is a simple, clever bedside trick — placing a cold pack on droopy eyelids for a few minutes can temporarily improve muscle strength, helping doctors confirm the diagnosis easily and painlessly.
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Definition:
Myasthenia gravis is an autoimmune disease causing muscle weakness die to neurological disfunction.
Causes:
May be due to genetic factors and any viral infection.
Symptoms:
Muscle weakness, double vision, drooping of eyelid, difficulty in speaking.
Treatment:
Medications like Cholinesterase inhibitors, corticosteroids, Immunosuppressants. Blood transfusions. Surgery like thymectomy.
Ice Pack Test:
It’s mainly to detect drooping of eyelid.
Apply an ice pack to the affected eyelid for a few minutes.
If the eyelid opens further after the ice pack application -Myasthenia gravis is positive.
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Nice explanation
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“Myasthenia Gravis = Mind to Ground”
(Descending muscle weakness: starts in the face, goes down)
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Order of Muscle Involvement in Myasthenia Gravis:
-
Ocular muscles – ptosis, diplopia (most common initial presentation)
-
Bulbar muscles – dysarthria, dysphagia, difficulty chewing
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Proximal limb muscles – weakness in shoulders, hips
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Respiratory muscles – in severe cases (myasthenic crisis)
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Myasthenia Gravis is an autoimmune disease where your body mistakenly attacks nerve muscle connections, causing muscle weakness.
Yes, I’ve heard of the Ice Pack Test, where applying ice can temporarily improve muscle strength, aiding in diagnosis.
In pharmacology terms, Myasthenia Gravis (MG) in which the number of acetylcholine receptors decrease, due to which the nerve transmission get decreased at neuromuscular junctions
Myasthenia Gravis is an autoimmune disorder causing weakness in skeletal muscles due to antibodies against acetylcholine receptors.
Yes, the Ice Pack Test temporarily improves ptosis by inhibiting acetylcholinesterase activity.
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Nice explanation
A good diagrammatic presentation.
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Informative