Dextromethorphan is a drug used in many over-the-counter cough and cold medicines for its antitussive effects.
It comes in oral strips, lozenges, liquids, or liquid-filled capsules and formulations often combine the drug with guaifenesin, acetaminophen, and pseudoephedrine.
What Happened?
In September 2025, several children in Rajasthan tragically lost their lives after consuming a cough syrup manufactured by Kaysons Pharma.
The incident triggered widespread panic and immediate government action.
Authorities responded by:
• Suspending the state drug controller
• Halting distribution of all 19 products from Kaysons Pharma
• Temporarily banning all dextromethorphan-containing syrups pending safety review
An expert committee has been established to investigate the cause and ensure the safety of all similar formulations across India.
Government and Public Health Response
The Indian drug regulatory bodies have intensified inspections, initiated quality audits, and announced stricter norms for labeling, testing, and pharmacovigilance.
Meanwhile, other regions, such as Chandigarh, have clarified that none of the affected batches were distributed locally, reassuring public safety.
Why It Matters
This incident highlights the urgent need for stronger drug quality control, pediatric safety monitoring, and transparency in pharmaceutical manufacturing.
Dextromethorphan is used globally for cough suppression, but improper formulation or contamination can have fatal outcomes especially in children.
The Dextromethorphan controversy serves as a wake-up call for the entire healthcare system.
MBH/AB
