CRISPR in the clinic: where are we now?

[Ayushi32]

Once a futuristic concept, CRISPR gene editing is now making its mark in real-world medicine. From curing rare genetic disorders to engineering immune cells to fight cancer, CRISPR is stepping out of the lab and into the hospital.

Landmark Success:
In 2023, the first CRISPR-based therapy for sickle cell disease received regulatory approval in the UK and USA. This therapy edits a patient’s own stem cells to produce healthy red blood cells—offering a potential cure rather than lifelong management.

Cancer Trials:
CAR-T cells enhanced using CRISPR are being tested in clinical trials for leukemia and solid tumors, showing promising results with fewer off-target effects.

Beyond Genetics:
New trials are exploring CRISPR in infectious diseases (like HIV), eye disorders, and even cardiovascular diseases by targeting genetic risk factors.

Would you consider a CRISPR-based treatment if it were offered to you or a loved one? What excites or worries you about this technology?

[Rashichauhan]

In my opinion, CRISPR is a big medical breakthrough — I’d consider it if it’s safe and needed, but strict safety and ethics are a must.

[LikhithaReddy]

CRISPR sounds like a big step forward in medicine. The idea that we can fix diseases by changing our own cells is really amazing. If it can help save a life or give someone a better future, But yes, it also makes me a little nervous because it’s still new. But with proper care and research, this can really change the way we treat serious health problems.

[Rachana]

CRISPR is also being explored for non genetic diseases. Researchers are investigating its use in treating chronic conditions like heart disease and blindness.

[Priyadharshini]

Crispr is one of the great development in the science field. In recent study it is shown that it is used to align DNA sequences in the cancer cells.

[Yash1612]

Absolutely, I would consider a CRISPR based treatment especially if it is for a serious or life threatening condition