CRISPR-Cas9: Revolutionizing Precision Medicine in Biotechnology

Biotechnology
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CRISPR-Cas9 has become a central genome-editing platform in molecular biotechnology, enabling sequence-specific DNA editing in a highly efficient and relatively simple manner. Its use has greatly improved functional genomics because it enables the knockout, insertion, and correction of specific genes to speed up disease modeling and target validation. CRISPR-based approaches are being explored in translational studies in the treatment of monogenic disorders, oncology, and immunotherapy, as well as engineered T-cell methods. Continued studies have been done to enhance editing fidelity, reducing off-target effects, and to construct future CRISPR systems that would be very important in the future of precision therapeutics.

https://www.nature.com/articles/s41392-023-01309-7

MBH/AB

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It’s fascinating how virus hijacks our cells to create disease while humans can now hijack bacteria’s immune system to protect ourselves or correct our disorders.

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CRISPR is a great technology that could revolutionize the medical field. Being able to modify genes—the very core of our existence—could help provide personalized treatment options. Modifying and applying this technology requires responsible decisions made by scientists with proper clinical trials.

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Well stated. CRISPR-Cas9 has transformed functional genomics and translational research, and ongoing improvements in precision and safety will be key to its role in future gene based therapies.