A new study gives a direction for the upper boundaries of human life span, suggesting that even under the most favorable conditions, DNA mutations may still limit life to 146–194 years. The strongest evidence for living longer and healthier comes from established lifestyle measures, including regular exercise, quality sleep, and a healthy diet.
So my concern is- Is there a biological limit on human life span? What if there isn’t any?
Researchers for a long time continue to debate this question, whether current or future therapies could continue extend your life for some more years. New research suggests that inevitable biological processes may place a ceiling on human life.
Researchers based in Russia built a computerized model designed to isolate one of aging’s most fundamental biological process: the accumulation of somatic mutations. Unlike inherited genetic mutations, somatic mutations occur after birth. Every time DNA is copied or damaged by healthy cellular activity, small errors can occur. Most are harmless, but over time, these mutations accumulate and may eventually impair cellular function or lead to cancer.
When the investigators combined four critical organ systems into a single model, they estimated a median life span of approximately 156 years, with a range of 146 to 194 years. Using this same modeling technique, researchers estimated a maximum life span of 210 to 557 years. Those numbers far exceed the current longest verified human life span of 122 years.
Although researchers continue searching for therapies that directly target biological aging, experts emphasize that the strongest evidence still supports familiar lifestyle measures.
Regular physical exercise is consistently considered as one of the most effective interventions for improving health span. The benefits of exercise include reducing the risk of cardiovascular disease, diabetes several cancers, and [cognitive decline while preserving muscle strength, mobility, and independence with age.
Other important factors for improving health span include:
- maintaining healthy blood pressure
- lowering LDL cholesterol
- good sleep habits
- social interaction and relationships
Do you think that in near future we can control this too? And if it’s possible and you will be asked for its clinical trial would you agree for it?
MBH/PS