Beyond the Report: Why "Normal" Isn't always healthy?

In the lab, we often see results that fall within the “biological reference range.” But as an MD Biochemist, I’m learning that a number on a page is only 10% of the story.

Biochemistry is the study of life at the molecular level, yet we often treat it like a snapshot rather than a movie. Whether it’s subtle shifts in thyroid function or the early markers of metabolic stress, the real “diagnosis” happens in the trend, not just the single test.

As medics, we are trained to look for pathology, but I’m becoming more interested in the biochemistry of wellness.

How do we optimize the system before it breaks?

Do you think our current medical education focuses too much on treating the “abnormal” result and not enough on understanding the person behind the “normal” range?

MBH/AB

This is such an important reminder! “Normal” lab values don’t always mean optimal health- context, symptoms, and individual variation matter just as much. A holistic view often reveals what numbers alone can’t show.

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Should we move toward using more sensitive functional markers, or would that lead to over-medicalizing patients who are technically within range? What do u think?