A rare case of recurrent urinary tract infection (UTI) lasting ~1.5 years.
Clinical course 
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Age: 19 yo, female

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No history of genetic/metabolic disorders. No history of UTI.
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Patient has PCOD
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Sexually inactive
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Initially started with burning micturition

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Treated empirically with multiple antibiotics including Amoxicillin & clavulanic acid + probiotics first 7 days

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After recurrence, urine culture showed E. coli
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Treated with Nitrofurantoin (5 days) + probiotics

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Despite this, monthly recurrences continued for ~1 year
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Each episode managed again with Nitrofurantoin.
Progression:
Over time, symptoms progressed beyond dysuria to:
Urinary urgency and frequency
Loss of urinary control (incontinence)
Possible sphincter dysfunction or bladder involvement
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Investigations: USG KUB: Normal
(throughout the case from the first episode) -
Resolved post nitrofurantoin dosage 7 days + probiotics 30 days.
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Patient saw recurrence after every 3-4 months and eventually she was free of recurrent UTI after 2 yrs.
What research suggests for recurrent UTI ? 
Recurrent UTI (≥2 in 6 months or ≥3/year) often requires more than repeated short antibiotic courses. Guidelines suggest:
Urine culture before each treatment (to confirm organism + sensitivity)
Targeted antibiotic therapy based on culture sensitivity
Consider longer prophylaxis in selected cases (low-dose antibiotics)
Evaluate for underlying causes, such as:
- Incomplete bladder emptying
- Kidney/bladder stones
- Structural urinary tract issues
- Diabetes or immunosuppression
- Sexual activity–related reinfection
Open discussion:
What could have been done differently in management and why did recurrence persist despite the us of nitrofurantoin?
Clinical reflection ![]()
Recurrent UTI is often not a single-pathogen problem, but a cycle of infection, host response, bladder function and microbiology.
MBH/PS