You may have heard of IVF or surrogacy, but what if a baby could be born with DNA from three people?
That’s exactly what’s happening with Mitochondrial Replacement Therapy (MRT)—a technique where a baby is created using genetic material from three individuals:
Nuclear DNA (99.8%) comes from the mother and father
Mitochondrial DNA (0.2%) is taken from a donor woman
Why Is This Done?
Some women carry mitochondrial diseases—genetic disorders passed down through defective mitochondria. These diseases can cause muscle weakness, heart problems, neurological damage, and even death in babies.
MRT was developed to prevent the transmission of such diseases, giving parents a chance to have healthy biological children.
How Does It Work?
1. Mother’s egg (with faulty mitochondria) has its nuclear DNA removed
2. A donor egg (with healthy mitochondria) also has its nucleus removed
3. Mother’s nuclear DNA is inserted into the donor egg
4. This egg is fertilized with the father’s sperm → creating an embryo
The resulting baby carries:
Traits (eye color, height, etc.) from mother and father
Mitochondrial health from the donor woman
Where Is It Done?
The first baby was born using this technique in Mexico (2016)
The UK became the first country to legally approve it under strict regulations
Recently, babies using this technique have been born in Greece, Ukraine, and a few other countries
Would you support this if it could prevent deadly genetic diseases? Or do you think it interferes too much with natural reproduction?
Let’s hear your thoughts!