This new combination Reduces fat and preserves lean mass !

General
1

A recent clinical study has grabbed attention in the obesity treatment space. The combination of bimagrumab + semaglutide led to:

  • 22.1% average body weight reduction in 72 weeks
  • 92.8% reduction in fat mass (vs 71.8% with semaglutide alone)
  • Better muscle preservation (only 2.9% lean mass loss vs 7.4% with semaglutide alone)
  • 21.7 cm drop in waist circumference

This means the therapy not only helps with weight loss but specifically targets harmful abdominal fat while protecting muscle mass.

What do you think ?

Should this dual approach become the future of obesity management, or do the long-term risks/costs still need careful evaluation?

6 Likes
2

New to me thanks for the information

3

Semaglutide only helps in weight loss . Combination of both the drugs helps weight loss reduction of lean mass also this would be a-great approach for health care professional to treat the patient

4

Interesting and informative. This is very new topic to me. But studying it would really benefit many healthcare professionals to treat patients.

5

The study results look very promising, especially the muscle preservation part, which is a rare focus in obesity care. But, personally, the long-term safety, cost, and accessibility will decide whether this combo becomes the golden treatment of obesity management.

6

This is new to me, but impressive! Protecting muscle while losing fat is a big plus, though long-term safety and cost still need study.

7

I think it’s important to see how safe it is in the long run and whether it will be affordable for most people. If those things work out, this approach could really be a game changer.

8

The combination of bimagrumab and semaglutide resulted in significant fat mass reduction, including visceral fat, while lean mass was largely preserved,These findings further support the investigation of the activin pathway inhibitor to optimize the degree and quality of weight reduction for people living with obesity.

9

If this helps many patients out there with less or no side effects i would love to implement it on patients soon with all requirements.

10

New topic to read… I think it needs more research to check the safety evaluations and long term effects.

11

Informative!