Tell me about pathology of cardiomyopathym.
Cardiomyopathy is a disease of the heart muscle.
Types include dilated, hypertrophic, restrictive, and arrhythmogenic.
Pathological features include myocyte hypertrophy and disarray.
Fibrosis and inflammation are common findings.
Genetic mutations and viral infections can cause cardiomyopathy.
Toxic exposure, such as alcohol, can also contribute.
Heart failure, arrhythmias, and sudden cardiac death can occur.
Cardiomyopathy can lead to impaired heart function.
Diagnosis involves clinical evaluation and imaging studies.
Treatment aims to manage symptoms and slow disease progression.
1 Like
Cardiomyopathy
→ Dilated (DCM)
• 4-chamber dilation
• Flabby heart
• Myocyte hypertrophy + fibrosis
• Causes: Genetic, Alcohol, Viral, Drugs
• Systolic dysfunction ↓ EF
→ Hypertrophic (HCM)
• Asymmetric septal hypertrophy
• Small LV cavity
• Myofiber disarray
• Cause: Sarcomere mutations (AD)
• Diastolic dysfunction
→ Restrictive (RCM)
• Rigid ventricles, normal size
• Fibrosis/Infiltration (Amyloid, Iron)
• Diastolic dysfunction
• Causes: Amyloidosis, Hemochromatosis, Loeffler’s
1 Like
