Rapid MCQ of the day- 11/02/2026

General
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Aspirin
Aspirin612×408 27 KB

Which property of platelets is responsible for the prolonged antiplatelet effect of aspirin?

  • High thromboxane content
  • Presence of CYP enzymes
  • Absence of nucleus
  • Rapid turnover
  • High prostacyclin synthesis
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Drop down in the comments, the complete mechanism and the dose for antiplatelet action.

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In short - By inhibiting COX-1 > TXA₂ levels fall > platelet aggregation decreases.
Since platelets have no nucleus they can’t resynthesize COX - 1 = The antiplatelet effect lasts for the entire lifespan of the platelet (7–10 days).

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:smiling_face: Great @DMdoc. You’ve explained it well. What dose do you think Aspirin has antiplatelet action? :thinking: