Pharmacology time......are you ready? - Therapeutic Drug Monitoring

Which drugs require therapeutic drug monitoring???

You know TDM?
Why is it necessary?

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All TCA, Phenytoin, Digoxin, Lithium, Barbiturates, A lot of anti-epileptics and Antipsychotics.

Yes
To prevent toxicity due to high dose, majority exhibit 0 order kinetics and can easily cross the Narrow Therapeutic Window and prove dangerous

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Theophylline
Gentamicin

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Therapeutic drug monitoring necessary for dose adjustment and measuring toxicity

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  • Lithium
  • Phenytoin
  • Theophylline
  • Warfarin
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digoxin
amikacin
methotrexate
vancomycin
gentamycin
more..
required TDM , all are present in a list given by govt. to hospital authority and present online also

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