Non-coding RNAs - Are they really a junk ?

A non-coding RNA (ncRNA), also called the junk RNA is a functional [RNA] molecule that is not translated into a protein. The amount of DNA contained inside each cell is vast and not all of the genetic sequences present within a DNA molecule actually code for a protein. In fact, over 98% of the human genome is non-coding DNA.

It appears that non-coding DNA can be broken down into 3 components: Regulatory regions for genes , Areas that code for RNA molecules that are used by our cells for functions other than coding for proteins and Non-functional DNA.

Do you really think Non-coding RNAs are junk ?

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Good post👍
No,they aren’t any junk,it can be significant in identifying gene expression and disease control.

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Non- coding RNA’s are not turned to proteins. But, they regulate gene expression and some cellular process such as cell growth, differentiation, and disease pathogenesis.

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Even if they don’t code, they have lot of significant functions to perform.

  • They are very essential for protein synthesis and form major part of ribosomes .
  • During translation, they carry amino acids to the ribosome with them
  • They also modify other Rna with help of methylation.
  • They are also involved in rna interference.
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Honestly, no — not at all.
The term junk RNA feels outdated now. Just because something doesn’t make proteins doesn’t mean it’s useless. Non-coding RNAs actually do a lot behind the scenes like helping control gene expression, guiding cell processes and keeping our biology in balance.
It’s a bit like the backstage crew in a play. You may not see them on stage but without them, the whole show would fall apart.
So no, they’re not junk. They’re just misunderstood.

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In the evolution, RNAs were the initial genetic materials. Over the time they got replaced by DNA. That however does not diminish the significance of RNAs in any way.
And this is a story of millions and millions of years. So all respect to RNA!

#Biology #Evolution #Darwin #Mendel

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