INTRODUCTION:
HIV is a long-term infection that needs continuous treatment. Many patients feels it difficult to take medicines every day, and some develop resistance to common HIV drugs. Lenacapavir is a new medicine that helps in such difficult cases.
ORIGIN AND APPROVAL:
Lenacapavir was developed by Gilead Sciences it is an American biopharmaceutical company in Foster City, California. It was approved by the US FDA in 2022. The brand name of lenacapavir is (Sunlenca, yeztugo) It is mainly used for patients who already have resistance to many HIV medicines.
Lenacapavir belongs to: *Antiretroviral drugs,*HIV-1 capsid inhibit. It is the first drug in this group.
MECHANISM OF ACTION:
THERAPEUTIC USES:
Used to treat HIV-1 infection, Helpful in multi drug-resistant HIV, Given to treatment-experienced adults, Always used with other HIV medicines.
ADVERSE EFFECT:
Pain or swelling at injection site, Nausea, Headache, Tiredness,
Rare side effects:
*Allergy
*Increased liver enzymes.
IMPORTANT OF LENACAPAVIR:
*Acts at many stages of HIV life cycle
*Works even when other drugs fail
*Improves patient compliance
CONCLUSION:
Lenacapavir is a new, long-acting HIV medicine that is very useful in patients with drug-resistant HIV. Its 6-months injection schedule for per year 2 times and make unique action. it is the most important drug in modern HIV treatment.
WHAT DO YOU THINK ABOUT THIS DRUG ?
MBH/PS