Japan’s New research- humans can regrow third set of teeth- A Rise of new hope

I lost hope when I had to sacrifice a tooth affected by caries. Now, I have to get an artificial tooth implant that costs nearly a lakh rupees. It has affected me financially. Recently, I came across new research on regrowing teeth, and it gave me a ray of hope.

I heard the news, a Japanese scientist Dr. Katsu Takahashi, a leaf scientist of medical research institute Kitano Hospital in Osaka, Japan has been studying the genetic principles of tooth development for years.

The researchers found that the USAG-1 protein could limit the growth of teeth in mice. Therefore, ensuring that the protein did not form could potentially invite teeth to grow, they concluded. The team developed a medication to block the protein and then successfully allowed mice to grow new teeth.

A 2023 paper published in Regenerative Therapy1 addresses the lack of treatments available for tooth regrowth, but the study suggests the anti-USAG-1 antibody treatment in mice could offer a “breakthrough” for humans.

About 1 percent of humans suffer a genetic condition, anodontia, that prevents a full set of teeth from growing. Researchers now believe there is hope for tooth regrowth in humans after the successful results with mice in the trials.

The scientists, noting that humans have a third set of teeth available as buds and ready to grow as needed, are even more encouraged about the possibilities.

For more details:

https://www.dentistrytoday.com/researchers-in-japan-discover-medicine-capable-of-regrowing-third-set-of-teeth-for-humans/

MBH/PS

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This could be a fascinating step toward regenerative oral medicine

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Great discovery indeed if happens..

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I feel this research gives hope that future dental treatments may become more natural and affordable for patients with tooth loss.

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A drug for the same purpose—to regrow the teeth—has been developed by Japanese researchers, and I read in the news that it has also been set for a clinical trial. All I have to say is the future of dentistry is really very bright with the advent of this new research. Read more about this drug here: Japan Begins Human Trials for Tooth Regrowth Drug TRG-035

Yes @niharika17

Tooth decay and the treatment is very scary and very costly. Because of the new research dental treatment will be cost effective and less painful.

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Yes @DrPal_28

Yes definitely @Kartikkandalkar

True @Bansi

Definitely @Ashana

Thank you for sharing. It’s very insightful.

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Glad you found it insightful @Snazir

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A hopeful shift from implants to biology—exciting to see where this research goes.

Great progress, though still in early stages. Looking forward to human applications in the future.

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Hopeful shift to biology- exciting times ahead.

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Nowadays mostly people are suffering from dental carries and cavity .

Therapies and transplant cost are very high so this regrowing of third teeth is better replacement method.

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Let’s hope for it @AmiyaSrivastava

Yes @Vishal5065yadav

Definitely @Yashi_Sachan

Yes @Mansi_Tiwari