A 12-day-old male baby born to a 27-year-old primigravidae mother at 38 + 2 weeks gestation via cesarean section presented with complaints of fever, poor feeding, and excessive crying for 4 days. In addition, parents noticed increasing facial hyperpigmentation. No history of maternal fever or any other antenatal complications were reported. Apgar scores were 8 and 9 at 1 and 5 minutes, respectively. Birth weight was 2.76 Kg. The baby was discharged on breastfeeds
on day 3 of life. On 8th day of life, infant developed fever, poor feeding, excessive crying, and facial hyperpigmentation.
At admission, baby was febrile (temp. 100.1F/37.8°C), irritable, and had hyperpigmentation of face.
Prompting questions for discussion:
- Most likely diagnosis and the specific sign associated/pathognomic: what feature in the image supports diagnosis?
- Key differentials for neonatal hyperpigmentation with recent maternal febrile exanthem?
- What bedside clues help separate these?
- What initial workup would you prioritize?
MBH/DB
