Hirschsprung’s disease, or congenital intestinal aganglionosis, is a lack of nerve cell bodies (ganglion cells) in a segment of the bowel. This interferes with the coordinated squeezing action called peristalsis, which normally moves intestinal contents forward.
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New disease learned today.
Understanding how the absence of nerve cells disrupts peristalsis really highlights the importance of early diagnosis and specialized care to help children lead healthy lives.
Due to the lack of ganglion cells, Hirschsprung’s disease is a dangerous congenital disorder that impairs regular bowel movements. Effective peristalsis is impeded by this lack of nerve coordination, which can result in severe constipation, distension of the abdomen, and possible complications such as enterocolitis. In order to restore bowel function and shield afflicted children from long-term gastrointestinal problems, early diagnosis and surgical intervention are essential.