# \#rna-interference

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## [Zilebesiran: A First-in-Class RNAi Therapy for Hypertension](https://www.medboundhub.com/t/zilebesiran-a-first-in-class-rnai-therapy-for-hypertension/8932)

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**Author:** [@Nikunj](https://www.medboundhub.com/u/Nikunj)\
**Replies:** 2\
**Last updated:** [September 25, 2025, 2:54pm UTC](https://www.medboundhub.com/t/zilebesiran-a-first-in-class-rnai-therapy-for-hypertension/8932 "2025-09-25T14:54:45Z")

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Zilebesiran is an investigational small interfering RNA (siRNA) therapy developed by Alnylam pharmaceuticals for mild to moderate hypertension. :right\_arrow: M.O.A: It targets angiotensinogen (AGT) in the liver, suppre…