# Drug of the week series - 21.3

**URL:** <https://www.medboundhub.com/t/drug-of-the-week-series-21-3/23272>\
**Category:** General\
**Created:** [September 10, 2026, 7:01am UTC](https://www.medboundhub.com/t/drug-of-the-week-series-21-3/23272 "2026-09-10T07:01:35Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Unnati](https://yyz1.discourse-cdn.com/flex033/user_avatar/www.medboundhub.com/unnati/32/5082_2.png) [@Unnati](https://www.medboundhub.com/u/Unnati)\
**Post date:** [September 10, 2026, 7:01am UTC](https://www.medboundhub.com/t/drug-of-the-week-series-21-3/23272/1 "2026-09-10T07:01:35Z")

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A patient who was on naltrexone develops severe pain after an emergency procedure. The medical team suggested to use opioid analgesics to relieve him from pain. Can you tell the most important factor to be taken under consideration before prescribing the same?

_Poll ([view on site](https://www.medboundhub.com/t/drug-of-the-week-series-21-3/23272/1))_

Answer to the day 2 poll (21.2) poll: B. Confirm an adequate opioid-free period before starting

MBH/PS

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**Author:** ![ayushinarang](https://yyz1.discourse-cdn.com/flex033/user_avatar/www.medboundhub.com/ayushinarang/32/5772_2.png) [@ayushinarang](https://www.medboundhub.com/u/ayushinarang)\
**Post date:** [September 10, 2026, 9:00am UTC](https://www.medboundhub.com/t/drug-of-the-week-series-21-3/23272/2 "2026-09-10T09:00:21Z")

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Naltrexone is an opioid antagonist meaning it blocks the receptors opioids bind to, so opioids as analgesia wouldn’t work for this patient anymore.