Drug of the week series - 20.1

What is the Mechanism of Action of Drug Saroglitazar, Which is most commonly used in Metabolic Associated Steatohepatitis?

  • A. Predominant PPAR-γ activation → increased insulin sensitivity + decreased triglycerides
  • B. Predominant PPAR-α activation + moderate PPAR-γ activation → improved lipid metabolism + insulin sensitivity
  • C. PPAR-α antagonism + PPAR-γ activation → reduced hepatic gluconeogenesis
  • D. PPAR-α activation + GLP-1 receptor agonism → increased insulin secretion + triglyceride reduction
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